RT - Journal TY - JOUR A1 - Qadri, Shagufta A1 - Shams, Asfa A1 - Alam, Kiran A1 - Irfan, Sarah T1 - Papillary carcinoma thyroid evolving within struma ovarii: An unusual occurrence YR - 2019/1/1 JF - International Journal of Histopathological Interpretation JO - Int J Histopathol Interpret SP - 11 OP - 15 VO - 8 IS - 1 UL - https://www.ijhi.org/article.asp?issn=WKMP-0130;year=2019;volume=8;issue=1;spage=11;epage=15;aulast=Qadri;t=5 DO - 10.4103/ijhi.IJHI_2_21 N2 - Struma ovarii is a monodermal variant of ovarian teratoma. It is a very rare, germ cell tumor of the ovary, constituting less than 1% of all ovarian tumors. Thyroid tissue is the predominant element, constituting more than 50% of the total. Thyroid-type carcinoma arising in struma ovarii is a rare finding, of which papillary carcinoma being more common, followed by follicular carcinoma and a newer entity termed as highly differentiated follicular carcinoma of ovarian origin. A case of 48-year-old female presented with complaints of acute lower abdominal pain and vaginal bleeding. Imaging showed a solid cystic mass in left adnexa whereas right adnexa was unremarkable. Left salpingo-oophorectomy was performed. Histopathological examination and subsequent immunohistochemistry revealed struma ovarii with neoplastic transformation into papillary thyroid carcinoma. Malignant struma ovarii is difficult to diagnose clinicoradiologically and is mostly discovered incidentally, with only handful of cases published in the literature. ER -