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ORIGINAL ARTICLE
Year : 2018  |  Volume : 7  |  Issue : 1  |  Page : 1-7

Morphological features in granulomatous mastitis: A window to the etiopathogenesis


1 Department of Pathology, Vardhman Mahaveer Medical College & Safdarjung Hospital (VMMC & SJH), New Delhi, India
2 Department of Surgery, Vardhman Mahaveer Medical College & Safdarjung Hospital (VMMC & SJH), New Delhi, India

Correspondence Address:
Meetu Agrawal
Department of Pathology, Vardhman Mahaveer Medical College & Safdarjung Hospital (VMMC & SJH), New Delhi.
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijhi.ijhi_4_20

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Background: Granulomatous mastitis holds a special place amongst the various non-neoplastic lesions of breast. Most granulomas at various sites are thought to be and turn out to be tubercular, especially in a high tuberculosis prevalence country. However, a physiologically dynamic organ-like breast can have granulomas due to various causes, which have different therapeutic implications. Further, these lesions are usually mass-forming and close mimickers of malignancy. A careful analysis of histopathology can provide important clues to the etiopathogenesis. Aims: The aim of this study was to perform a detailed histopathological examination of cases of granulomatous mastitis and correlate it with clinical characteristics and follow-up data wherever applicable. Materials and Methods: A retrospective analysis of cases retrieved was carried out by two pathologists (RPS and MA). The morphological details were analyzed against the clinical, surgical, and follow-up data. Results and Conclusion: With careful analysis, the nature of constituent cells, relative proportion of cells and associated pathological findings can provide a clue as to the etiology of granulomas.


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